Tadalafil does not permanently increase penis size. The medication improves blood circulation and erection quality, which may create the impression of temporary enlargement.
Tadalafil is a widely used medication for treating erectile dysfunction and also draws attention for its impressive sales numbers.
In 2024, 61.2 million units were sold in Brazil, according to a report from the Federal Pharmacy Council.
Despite its popularity, there are still many questions about its effects.
Below, understand how tadalafil works in the body, what its effects are, and learn about treatments that can actually promote penis enlargement.
Does tadalafil increase penis size?
No. Tadalafil does not increase penis size.
In some specific situations, such as after prostate removal (radical prostatectomy), the medication can help preserve penile tissue and reduce fibrosis formation.
A study that evaluated the effects of tadalafil after radical prostatectomy compared three groups of patients who underwent total prostate removal with nerve preservation:
- tadalafil 5 mg daily;
- tadalafil on demand;
- placebo.
After 9 months of follow-up, patients who used tadalafil daily showed less loss of penile length compared to the placebo group. But this does not mean the medication increases penis size.
The authors explain that penile shortening is a relatively common complication after prostatectomy, resulting from reduced tissue oxygenation and fibrosis development.

How does tadalafil work in the body?
Tadalafil is a medication used to treat erectile dysfunction. The substance does not cause spontaneous erections or increase sexual desire. Its function is to facilitate erection when there is sexual stimulation.
During arousal, the brain sends signals to the penis that stimulate the release of nitric oxide — a substance responsible for relaxing blood vessels in the region. This causes arteries to dilate, more blood enters the corpora cavernosa — structures that give rigidity to the penis — and an erection occurs.
The body also produces an enzyme called PDE5, which interrupts this process by reducing the action of these substances. Tadalafil blocks the action of this enzyme, allowing blood vessels to remain relaxed for longer and blood flow to be sufficient to achieve and maintain an erection.
Therefore, the medication only works when there is sexual arousal. Without stimulation, tadalafil does not cause an erection.
Who can use tadalafil?
It can be indicated for adult men with erectile dysfunction, benign prostatic hyperplasia, or in specific situations, pulmonary arterial hypertension.
Tadalafil should only be used under medical guidance. Evaluation is essential to check for possible contraindications and reduce the risk of adverse effects, especially in people with cardiovascular diseases.
Related: Tadalafil in young men: understand the risks of use without medical guidance

Is there any medication that increases penis size?
No. Currently, there is no medication capable of increasing penis size.
What exists are treatments indicated for specific situations, such as hormonal changes that compromise penile development or protocols aimed at preserving length after certain urological surgeries.
Hormonal treatment
Indicated for boys with testosterone deficiency or changes in the action of sex hormones during childhood and puberty, with the goal of stimulating penile growth.
In adults, this treatment does not promote penis enlargement, except in cases of proven hormonal deficiency, when its goal is to restore hormone levels and not increase the organ.
Traction devices
Penile traction therapy does not spontaneously increase the penis, but can be prescribed in specific situations to preserve or recover penile length, especially after urological surgeries or in the treatment of Peyronie’s Disease.
Tadalafil and sexual performance: what is the relationship?
Tadalafil has an important association with sexual performance, as it can provide better quality erections and longer-lasting erections for men.
This is essential for sexual relations, especially for penetration. However, good performance does not depend solely on the medication.
Emotional control, partner compatibility, and anxiety management are also important for a satisfying sexual life.
Is there any medication that increases penis size?
No medication exists that increases penis size. Medications like Tadalafil and Sildenafil help men achieve a firm and lasting erection, but they do not make the penis grow.
Be wary of promises from medications that claim this result, as it is misleading advertising and can be harmful to your health.
Beware of miraculous promises
It is important to be skeptical of products, therapies, and devices that promise to increase penis size quickly and permanently.
Most of these methods lack scientific evidence and can pose health risks, in addition to creating frustration by setting unrealistic expectations about results.
Related: Does the tadalafil chip really work? Understand risks and facts
When to seek medical help?
See a urologist if you have concerns about penis size, difficulty achieving or maintaining an erection, changes in ejaculation, or any changes in penile anatomy.
Medical evaluation allows identification of possible causes of these symptoms, investigation of conditions such as hormonal changes, cardiovascular diseases, and other conditions that can compromise sexual health, as well as indicating the most appropriate treatment for each case.
Fill out the pre-analysis form to schedule your consultation and receive guidance from a specialist on sexual health treatment options.
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