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Does Taking Tadalafil Affect Ejaculation? Learn How the Medication Works

BY DR. PAULO EGYDIO · CRM-SP 67.482 · RQE 19514

Does Taking Tadalafil Affect Ejaculation? Studies Suggest It May Help Control and Timing

Many men ask whether those who take tadalafil ejaculate normally or take longer.

The medication is used to treat erectile dysfunction, and some research indicates it may also help in cases of premature ejaculation. However, other studies have found no significant difference in this respect.

See what science says about using tadalafil for premature ejaculation.

Does Tadalafil Influence Ejaculation?

There is still no consensus on how tadalafil might delay ejaculation, but the most accepted explanation is that it acts both on the sexual organs and on the brain.

The medication relaxes the smooth muscles of the male reproductive system. These muscles work involuntarily—without conscious control—and are present in several parts of the system, for example:

  • Vas deferens: responsible for transporting sperm;
  • Seminal vesicles: which produce part of the semen;
  • Prostate: a gland that contributes fluid to semen;
  • Urethra: the channel through which semen is expelled.

With these muscles relaxed, blood flow improves and sperm is not pushed with as much force, which could contribute to delaying ejaculation in some cases.

In addition, tadalafil reduces sympathetic-nervous-system activity, the system responsible for speeding up the heartbeat and triggering ejaculation. This mechanism can help maintain the erection longer and, consequently, postpone ejaculation.

A glass tipped on its side with blue capsules inside; in front, capsules that are half blue and half white.

Do People Who Take Tadalafil Ejaculate?

Yes, people who take tadalafil ejaculate normally. The medication does not affect orgasm or semen release.

It is prescribed for erectile dysfunction, yet studies show it may also be an option for premature ejaculation.

Tadalafil relaxes reproductive-system muscles and decreases sympathetic-nervous activity—linked to rapid arousal. This action may help maintain the erection longer and, in certain cases, contribute to delaying ejaculation.

What Do the Studies Say?

Several studies suggest that tadalafil works for premature ejaculation.

The first study analyzed 55 men with chronic premature ejaculation. Participants were randomly divided into two groups: one received a daily dose of 5 mg of tadalafil and the other a placebo.

The trial lasted three months, and researchers used questionnaires that measured the time from stimulation onset to ejaculation as well as validated diagnostic tools.

Results showed a better ejaculatory control among tadalafil users, but the statistical difference between groups was modest.

Another study investigated daily 5 mg tadalafil in men with erectile dysfunction and lower-urinary-tract symptoms. Sixty volunteers received the medication for three months.

Researchers applied three evaluation tools:

  1. International Index of Erectile Function (IIEF-5);
  2. Intravaginal Ejaculatory Latency Time (IELT);
  3. International Prostate Symptom Score (IPSS).

Daily use of 5 mg proved beneficial, though longer follow-up is needed to confirm results.

A black-and-white photo of an open book on a table with a pair of glasses resting on one page.

Side-Effects and Cautions When Using Tadalafil

The side-effects of tadalafil are classified as common or serious.

  • Common: headache, heartburn, nausea, diarrhea, flushing or tingling, pain in the stomach, back, muscles, arms, or legs;
  • Serious: priapism (an erection lasting more than three hours), blurred vision, hearing changes, chest pain, skin irritation or blisters, swelling of the face, throat, tongue, hands, feet, ankles, or legs.

The main precaution is to avoid self-medication and thus minimize these reactions.

To ensure safe use of tadalafil, a medical evaluation by a urologist—and, in some cases, a cardiologist—is essential.

Are There Other Alternatives?

Tadalafil is widely used to treat erectile dysfunction, and some studies point to potential benefits in cases of premature ejaculation.

However, it is essential to consult a urologist to determine the cause of sexual dysfunction and the most appropriate treatment.

Discover the treatment options available for each situation:

1. Premature ejaculation

Premature ejaculation may stem from emotional, physical, or combined factors. Common treatments include:

  • Sex therapy: indicated for anxiety, insecurity, or emotional conflicts;
  • Low-dose antidepressants: help increase the time to ejaculation;
  • Topical anesthetic gels: applied to reduce sensitivity and aid ejaculatory control.

2. Erectile dysfunction

Erectile dysfunction can be linked to physical or emotional causes, medications, and cardiovascular diseases such as diabetes and hypertension. Main treatments include:

  • Oral medications such as tadalafil and sildenafil, which improve blood flow to the penis and facilitate erection;
  • Vacuum devices that create pressure to stimulate an erection;
  • Therapy when erectile dysfunction stems from emotional factors like stress, anxiety, or low self-esteem;
  • Healthy habits such as quitting smoking, reducing alcohol consumption, eating well, and exercising regularly;
  • Penile prosthesis when there is no response to conventional treatments.

What to Expect When Using Tadalafil

With proper use as prescribed by a physician, many patients report improved erection quality, since the medication increases blood flow to the penis.

Although in some cases it may help delay ejaculation, tadalafil cannot be considered a specific medication for premature ejaculation; targeted treatment is needed for that dysfunction.

Tadalafil is an effective medication for erectile dysfunction. Stay on the blog to clear up your doubts about erection difficulties.

Learn more:

Written by

Dr. Paulo Egydio

Urologist · CRM-SP 67.482 · RQE 19514

Disclaimer: this article is for educational purposes only and does not replace a medical consultation. To evaluate your case, consult a specialist.

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    ABOUT THE AUTHOR

    Dr. Paulo Egydio

    Medical Director and Urologist at Egydio Medical Center. CRM-SP 67.482 · RQE 19514. Creator of the Egydio Technique, described in leading international urological guidelines.

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