Can people with Peyronie’s Disease take tadalafil?

Yes, people with Peyronie’s Disease can take tadalafil, especially when the disease is associated with erectile dysfunction.

What is the relationship between Peyronie’s Disease and erectile dysfunction?

The Peyronie’s Disease can affect erectile function because it causes changes in the structure of the penis, in addition to impacting the patient’s emotional health. Understand the relationship between Peyronie’s Disease and erectile dysfunction.

• Peyronie’s Disease forms scar tissue plaques in the tunica albuginea, a structure that surrounds and protects the cavernous bodies and helps block venous return, compressing the veins that would drain blood.
• The alteration of penis anatomy caused by the characteristic curvature of Peyronie’s Disease can compromise the expansion of the cavernous bodies, making it difficult for blood to reach the cavernous bodies, which contributes to the development or worsening of erectile dysfunction.

How does Peyronie’s affect erection?

The erection depends on the dilation of the cavernous bodies due to increased blood flow and also on the elasticity of penile tissues.

In Peyronie’s Disease, the formation of scar tissue plaques compromises this elasticity and modifies the anatomy of the penis, hindering its expansion during erection. As a result, some men may have difficulty obtaining or maintaining a rigid erection sufficient for sexual intercourse.

Physical and emotional impacts

Peyronie’s Disease can affect erectile function and quality of life in different ways.

In addition to physical changes due to the scar tissue plaque that causes the curvature and other changes, such as thinning or shortening, the condition can also generate emotional impacts that interfere with erectile function and relationships.

Understand how the emotional factor associated with Peyronie’s Disease interferes with the sexual health of men with this condition:

• Anxiety related to sexual performance that can increase the difficulty of obtaining or maintaining an erection.
• Reduced self-esteem due to dissatisfaction with the appearance of the penis.
• Fear of initiating sexual relations due to curvature or pain.
• Reduced intimacy and relationship conflicts, which can result in stress and depressive symptoms.

When does sexual function become compromised?

Peyronie’s Disease can compromise sexual function when penile curvature is pronounced or when it causes pain or discomfort during erection.

In these cases, it is essential to respect the body’s limits and avoid insisting on sexual intercourse or trying to correct the curvature manually, as this can worsen the injury and increase discomfort.

The recommendation is to see a urologist to assess the situation and define the treatment for Peyronie’s Disease.

Can people with Peyronie’s Disease take tadalafil?

Yes, people with Peyronie’s Disease can take tadalafil when there is erectile dysfunction associated with the disease.

When can the medication be indicated?

However, we must clarify that tadalafil does not improve Peyronie’s Disease. The medication improves the quality of erections because it promotes penile blood flow.

In what situations can the medication help?

Tadalafil can be useful in different situations related to Peyronie’s Disease, provided there is medical indication. Understand:

• When there is erectile dysfunction due to Peyronie’s Disease: tadalafil facilitates blood flow to the cavernous bodies during sexual stimuli, a mechanism involved in erection.

• When the quality of erection is compromised: the medication can improve penile rigidity, promoting sexual activity in men with less rigid erections because of penile curvature.

Related: Does tadalafil increase penis size?

When is medical evaluation necessary?

Evaluation with a urologist is recommended for all patients with suspected or confirmed diagnosis of Peyronie’s Disease.

The consultation allows confirming the diagnosis, assessing the severity of the curvature, identifying the presence of erectile dysfunction, and defining the most appropriate treatment.

In the evaluation, the doctor also analyzes the existence of contraindications to the use of tadalafil for Peyronie’s Disease, such as cardiovascular problems, changes in blood pressure, hepatic or renal diseases, or use of other medications that may interact with tadalafil.

What benefits can tadalafil bring to people with Peyronie’s?

Can I take tadalafil without medical guidance?

No. The use of tadalafil requires medical evaluation.

Although tadalafil has a good safety profile when prescribed correctly, self-medication can bring risks and mask health problems.

Medical evaluation is important because tadalafil should not be used by people who use nitrates for the treatment of heart diseases. The combination between tadalafil and nitrates can cause a marked drop in blood pressure, which reduces blood flow to vital organs.

Additionally, patients with severe hepatic or renal insufficiency also need evaluation before starting treatment. In these conditions, tadalafil can remain in the body for longer, increasing exposure to the medication and, consequently, the risk of side effects.

When to see a urologist?

See a urologist whenever there are anatomical changes and compromised functionality. Progressive curvature, pain during erection, and difficulty maintaining erection are signs that need to be investigated.

Investigation of symptoms by a specialist is essential to identify the origin of the problem and prescribe the most appropriate treatment.

Fill out the pre-analysis form to schedule your consultation with Dr. Paulo Egydio, urologist specialist in treatment for Peyronie’s Disease.