Ozempic is a medication indicated for the treatment of type 2 diabetes, which has gained popularity due to its weight loss effect. However, some men who used this medication reported erection difficulties. Is there a connection? Keep reading to discover what science has revealed so far.
The question of whether Ozempic causes erectile dysfunction is spreading on Reddit, a social network dedicated to discussions on various topics.
The medication for the treatment of type 2 diabetes gained popularity for its promise of rapid weight loss, and men who used it claim that their erections are no longer the same.
Like all medications, Ozempic can have side effects. But is there a relationship between its use and erectile dysfunction? Let’s explore what studies have indicated so far.
Does Ozempic Lower Testosterone?
Preliminary studies emphasize that among the sexual side effects of Ozempic are testosterone reduction and also erectile dysfunction.
This article published in The Journal of Sexual Medicine analyzed whether Ozempic lowers testosterone. The study focused on men aged 18 to 50 without diabetes who were prescribed Ozempic for weight loss after June 1, 2021, when semaglutide was approved for weight loss in non-diabetic and obese individuals.
The analysis excluded men with a history of prostate removal, diabetes, pulmonary hypertension, or pelvic radiation.
The investigation targeted 2,117 men without diabetes who used the medication to identify how many were diagnosed with erectile dysfunction at any point after using Ozempic.
The results indicate that men who used semaglutide were more likely to experience testosterone deficiency and erection difficulties. However, the authors emphasize that more research is needed to fully understand this relationship.
Still, the article’s authors stress the need for further studies to understand how semaglutide affects the reproductive hormones of non-diabetic men. They also emphasize that Ozempic’s hormonal side effects should be discussed between doctors and patients.
Does Ozempic Cause Erectile Dysfunction?
This article published in May 2024 in the International Journal of Impotence Research analyzed whether Ozempic could cause erectile dysfunction in obese, non-diabetic men.
The study focused on men aged 18 to 50 with a Body Mass Index (BMI) over 30, without diabetes, who received a prescription after June 1, 2021.
Patients with erectile dysfunction diagnosed with:
- phosphodiesterase-5 inhibitors;
- testosterone replacement;
- a history of testosterone deficiency;
- intracavernosal injections;
- penile prosthesis;
- a history of pelvic radiation;
- prostate removal;
- pulmonary hypertension;
- previous use of insulin or metformin
were excluded from the analysis.
The researchers compared 3,094 obese, non-diabetic men aged 18 to 50 who were prescribed semaglutide with the same number of obese, non-diabetic men without a prescription for this active ingredient.
The preliminary conclusion showed a risk of erection problems or new prescriptions for phosphodiesterase type 5 inhibitors, such as Viagra, one month after starting semaglutide.
Researchers also identified a higher probability of testosterone deficiency, with a 95% confidence interval.
The conclusion is that non-diabetic men prescribed semaglutide were more likely to experience erection difficulties and reduced testosterone levels.
What Are the Proven Side Effects of Ozempic?
The article “The excessive use of semaglutide (Ozempic) and its side effects in the quest for weight loss: a literature review“, analyzed 7 articles in Portuguese to list the main side effects of Ozempic.
This research explains that the most common reactions are:
- vomiting;
- diarrhea;
- fatigue;
- gallbladder problems, an organ that stores bile, a liquid produced by the liver that helps digest fatty foods.
The same article discusses the “rebound effect,” a situation where the body has adapted and no longer responds to the treatment, requiring a change in the medication dosage.
How to Minimize Proven Side Effects?
To minimize Ozempic side effects, some of the main recommendations are:
- Medical monitoring: Ozempic’s weight-loss effect is off-label, meaning it is “off-label” for the medication. Therefore, follow medical guidelines and report adverse reactions to your doctor;
- Consume foods that benefit sexual performance: foods like salmon, broccoli, and oats are excellent options to include in your diet. Additionally, consuming foods rich in vitamin D, an important nutrient for testosterone production, is essential;
- Exercise: Ozempic is not a miracle. To avoid the rebound effect, it is necessary to eat well and exercise.
Ozempic, used for treating type 2 diabetes, is increasingly sought after for weight loss. However, it is important to remember that in some cases, its use may be related to changes in male sexual health, as highlighted by some studies. Medical monitoring is essential to adjust treatment according to individual needs.
That’s why medical supervision is crucial, especially due to its potential impact on sexual health. A doctor can properly assess the risks, adjust the treatment, and suggest alternatives if side effects occur. Avoid self-medication to prevent complications and ensure that your weight loss or diabetes control journey does not negatively impact your quality of life and sexual function.
Want to know more? Stay informed with Dr. Paulo Egydio on TikTok and Kwai. Follow the urologist and take care of your health for a long and healthy life!
Learn more:
- Male Self-Care: Why Is It Important for Health?
- Learn All About Enlarged Prostate: Causes, Diagnosis, and Recommended Treatments
- Does Stress Decrease Libido? Learn How to Identify and Treat It
- What Is Ejaculation? Answers to Your Main Questions
- Consequences of Male Sexual Abstinence and the Problems It Can Cause
- 10 Tips for Penis Care to Maintain Health and Prevent Infections and Diseases
- See What Causes Erectile Dysfunction and Available Treatments
- Prostate Surgery: What to Expect, Risks, and Recovery
- Gut Health and Sexual Function: The Connection




